Publications 


Tok, S., Maurin, H., Delay, C., Crauwels, D., Manyakov, N. V., Van der Elst, W., Moechars, D. & Drinkenburg, W. H. I. M. (2022). Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L1666P amyloid mouse model of Alzheimers disease. Scientific Reports, 12, 7784. Download pdf  


Vandendijck, Y., Scott, J., Heerwegh, D., Van der Elst, W., Witek, J., Sinkha, R., & Fennema, H. (2022). Measuring respiratory syncytial virus infection severity in hospitalized children using the Pediatric Respiratory Syncytial Virus Electronic Severity and Outcome Rating System (PRESORS). Influenza and Other Respiratory Viruses. Download pdf  


Daniels, R., Van der Elst, W., Dieltjes, N., Appels, T., So, . K., Nys, T., Voeten, L., Breugelmans, P., Molenaar-de Backer, M. W. A., Gitz, E., Poole, S., & Patel, M. (2022). Validation of the monocyte activation test with three therapeutic monocolonal antibodies. ALTEX - Alternatives to Animal Experimentation. Download pdf 


Florez, A. J., Molenberghs, G., Van der Elst, W., & Alonso, A. A. (2022). An efficient algorithm to assess multivariate surrogate endpoints in a causal inference framework. Computational Statistics and Data Analysis. Download pdf Supplementary material 


Alonso, A. A., Van der Elst, W., Sanchez, L., Luaces, P., & Molenberghs, G. (2022). Identifying individual predictive factors for treatment efficacy. Biometrics, 78, 35-45Download pdf Supplementary material


Van Tetering, M. A. J., Jolles, J., Van der Elst, W., & Jolles, D. D. (2022). School achievement in early adolescence is associated with student’s self-perceived executive functons. Frontiers in Psychology, 12, 1-14. Download pdf


Van der Elst, W., Alonso, A. A., Coppenolle, H., Meyvisch, P., & Molenberghs, G. (2021). The individual-level surrogate threshold effect in a causal-inference setting with normally distributed endpoints. Pharmaceutical Statistics, 20, 1216-1231Download pdf Supplementary material


Ong, F., Wang, J., Van der Elst, W., Verbeke, G., Molenberghs, G. & Alonso A. A. (in press). Implementing the meta-analytic approach for surrogate endpoints in SAS and R: A word of Caution. Journal of Biopharmaceutical Statistics.


Rivera, D., Olabarrieta-Landa, L., Van der Elst, W., Gonzalez, I., Ferrer-Cascales, R., Penalver Guia, A. I., Rodriguez-Lorenzana, A., Galarza-del-Angel, J., Irias Escher, M. J., & Arango-Lasprilla, J. C. (2021). Regression-based normative data for children from Latin America: phonological verbal fluency letters M, R and P. Assessment, 28, 264-276. 


Lorenzo-Luaces, P., Sanchez, L., Saavedra, D., Crobmet, T., Van der Elst, W., Alonso, A. A., Molenberghs, G., & Lage, A. (2020). Identifying predictive biomarkers of CIMAvaxEGF success in non-small cell lung cancer patients. BMC Cancer.  Download pdf


Meyvisch, P., Alonso, A. A., Van der Elst, W., & Molenberghs, G. (2020). On the relationship between association and surrogacy when both the surrogate and true endpoint are binary outcomes. Statistics in MedicineDownload pdf 


Van der Elst, W., Alonso, A. A., Geys, H., Meyvisch, P., Bijnens, L., Sengupta, R., & Molenberghs, G. (2019). Univariate versus multivariate surrogate endpoints in the single-trial setting. Statistics in Biopharmaceutical Research, 301-310. Download pdf Supplementary material


Toornstra, A., Hurks, P. P. M., Van der Elst, W., Massar, K., Kok, G., & Curfs, L. M. G. (2020). Measuring goal setting in school-aged children: studying the effects of demographic variables in regression-based norms. Journal of Pediatric NeuropsychologyDownload pdf


Florez A. J., Alonso, A. A., Molenberghs, W., & Van der Elst, W. (2020). Generating random correlation matrices with fixed values: an application to the evaluation of multivariate surrogate endpoints. Computational Statistics and Data Analysis, 142. Download pdf Supplementary material


Toornstra, A., Hurks, P. P. M., Van der Elst, W., Kok, G., & Curfs, L. M. G. (2020). Measuring visual matching and short-term recognition memory with the CANTAB delayed matching to sample task in schoolchildren: effects of demographic influences, multiple outcome measures, and regression-based normative data. Child Neuropsychology, 26, 189-218. Download pdf


Alonso, A. A., Van der Elst, W., Molenberghs, G., & Florez, A. J. (2019). A reflection on the causal interpretation of individual-level surrogacy. Journal of Biopharmaceutical Statistics, 29, 446-467. Download pdf Supplementary material


Meyvisch, P., Alonso, A. A., Van der Elst, W., & Molenberghs, G. (2019). Assessing the predictive value of a binary surrogate for a binary true endpoint, based on the minimum probability of a prediction error. Pharmaceutical Statistics, 18, 304-315Download pdf Supplementary material


Alonso, A. A., Van der Elst, W., & Molenberghs, G. (2018). A maximum entropy approach for the evaluation of surrogate endpoints based on causal inference. Statistics in Medicine, 37, 4525-4538Download pdf Supplementary material


Alonso, A. A., Meyvisch, P., Van der Elst, W., Molenberghs, G., & Verbeke, G. (2019). A reflection on the possibility of finding a good surrogate. Journal of Biopharmaceutical Statistics, 29, 468-477Download pdf


Schraeyen, K., Van der Elst, W., Geudens, A., Ghesquière, P. & Sandra, D. (2019). Short-term memory problems for phonomes’ serial order in adults with dyslexia: evidence from a different analysis of the nonword repetition task. Applied Psycholinguistics, 40, 613-644.


Alonso, A. A., Van der Elst, W., & Meyvisch, P. (2017). Assessing a surrogate predictive function: a causal inference approach. Statistics in Medicine, 36, 1083-1098Download pdf Supplementary material


Rivera, D., Olbarrieta-Landa, L., Van der Elst, W., Gonzalez, I., Rodrigues-Irizarry, W., Carcia de la Cadena, C., & Arango Lasprilla, J. (2019). Normative data for verbal fluency in healthy Latin American adults: letter M, fruits, and occupation categories. Neuropsychology, 33, 287-300Download pdf 


Meyvisch, P., Kambili, C., Andries, K., Lounis, N., Theeuwes, M., Dannemann, B., Vandebosch, A., Van der Elst, W., Molenberghs, G., & Alonso, A. (2018). Evaluation of six month sputum culture conversion as a surrogate endpoint in a multidrug resistant tuberculosis trial. PLOS one, 13, i1-15Download pdf


Hermans, L., Molenberghs, G., Kenwards, M. G., Van der Elst, W., Nassiri, V., Aerts, M., & Verbeke, G. (2017). Clusters with random size: maximum likelihood versus weighted estimation. Statistica SinicaDownload pdf


Hermans, L., Nassiri, V., Molenberghs, G., Kenwards, M. G., Van der Elst, W., Aerts, M., & Verbeke, G. (2017). Fast, closed-form, and efficient estimators for hierarchical models with AR(1) covariance and unequal cluster sizes. Communications in Statistics - Simulation and Computation, 42, 1492-1505.  Download pdf


Van der Elst, W., Molenberghs, G., van Tetering, M., & Jolles, J. (2017). Establishing normative data for multi-trial memory tests: the multivariate regression-based approach. The Clinical Neuropsychologist, 31, 1173-1187Download pdf   Supplementary material 


Van der Elst, W., Molenberghs, G., Hilgers, R., Verbeke, G., & Heussen, N. (2016). Estimating the reliability of repeatedly measured endpoints based on linear mixed-effects models. A tutorial. Pharmaceutical Statistics, 15, 486-493. Download pdf   Supplementary material


Thijssen, A., Creemers, A., Van der Elst, W., Creemers, E., Vandormael, E., Dhont, N. & Ombelet, W. (in press). Predictive factors influencing pregnancy rates following intrauterine insemination with frozen donor semen: a prosprective cohort study. Reproductive Biomedicine.


Thijssen, A., Creemers, A., Van der Elst, W., Creemers, E., Vandormael, E., Dhont, N. & Ombelet, W. (in press). Predictive value of different covariates influencing pregnancy rate following intrauterine insemination with homologous semen: a prosprective cohort study. Reproductive Biomedicine.


Schraeyen, K., Van der Elst, W., Geudens, A., Ghesquire, P. & Sandra, D. (2017). Beyond global differences between monolingual and bilingual children on the nonword repetition task: retention skills for phonemes’ identity and serial order. Bilingualism: Language and Cognition, 21, 403–418.


Schraeyen, K., Geudens, A., Ghesquire, P., Van der Elst, W., & Sandra, D. (2017). Poor performance on the retention of phonemes’ serial order in short-term memory reflects young children’s poor reading skills. The Mental Lexicon, 12, 129-158.


Van der Elst, W. (2016). Statistical evaluation methodology for surrogate endpoints in clinical studies. PhD dissertation. Download pdf   Supplementary material


Alonso, A. A., & Van der Elst, W. (2016). The history of surrogate endpoint evaluation: single-trial methods. In A. A. Alonso et al. (Eds.), Applied Surrogate Endpoint Evaluation Methods with SAS and R. New York: CRC Press.


Alonso, A. A., & Van der Elst, W. (2016). Multiple trial methods for two continuous outcomes. In A. A. Alonso et al. (Eds.), Applied Surrogate Endpoint Evaluation Methods with SAS and R. New York: CRC Press.


Van der Elst, W., Alonso, A. A., & Molenberghs, G. (2016). The R package Surrogate. In A. A. Alonso et al. (Eds.), Applied Surrogate Endpoint Evaluation Methods with SAS and R. New York: CRC Press.


Van der Elst, W., & Molenberghs, G. (2016). Surrogate endpoints in rare diseases. In A. A. Alonso et al. (Eds.), Applied Surrogate Endpoint Evaluation Methods with SAS and R. New York: CRC Press.


Alonso, A., A., Van der Elst, W., Molenberghs, G., Buyse, M. , & Burzykowski, T. (2016). An information-theoreteic approach for the evaluation of surrogate endpoints based on causal inference. Biometrics, 72, 669-677Download pdf   Supplementary material


Van der Elst, W., Molenberghs, G., Alonso, A. A. (2016). Exploring the relationship between the causal-inference and meta-analytic paradigms for the evaluation of surrogate endpoints. Statistics in Medicine, 35, 1281-1298. Download pdf


Molenberghs, G., Alonso, A. A., Van der Elst, W., Burzykowski, Y., & Buyse, M. (2015). Statistical evaluation of surrogate endpoints in clinical studies. In W. R. Young & D. Chen (Eds), Clinical Trial Biostatistics and Biopharmaceutic Applications. New York: CRC press. Download pdf


Van der Elst, W., Hermans, L., Verbeke, G., Kenward, M. G., Nassiri, V., & Molenberghs, G. (2016). Unblanced cluster sizes and rates of convergence in mixed-effects models for clustered data. Journal of Satistical Computation and Simulation, 86, 2123-2139. Download pdf


Alonso, A., Van der Elst, W., & Molenberghs, G. (2015). Validating predictors of therapeutic success: a causal inference approach. Statistical Modelling, 15, 619-636. Download pdf


Buyse, M., Molenberghs, G., Paoletti, X., Oba, K., Alonso, A., Van der Elst, W., & Burzykowski, T. (2015). Statistical evaluation of surrogate endpoints with examples from cancer clinical trials. Biometrical Journal, 58, 104-132.  Download pdf


Martin, S., Mazzocco, C., Grosselin, A., Van der Elst, W., Dixon, R., Yannick, S., Brouillet, & Maury, P. (2015). Compensating for memory losses throughout adulthood: validation and normalization of the Memory Compensation Questionnaire for non-clinical French populations. Archives of Gerontology and Geriatrics, 60, 28-38. Download pdf


Alonso A., A., Van der Elst, W., Molenberghs, G., Burzykowski, T., & Buyse, M. (2015). On the relationship between the causal-inference and meta-analytic paradigms for the validation of surrogate endpoints. Biometrics, 71, 15-24. Download pdf   Supplementary material


Molenberghs, G., Alonso Abad, A., Van der Elst, W., Burzykowski, T., & Buyse, M. (2013). Surrogate endpoints: when should they be used? Clinical Investigation.


Van der Elst, W., Molenberghs, G., Van Boxtel, M. P. J., & Jolles, J. (2013). Establishing normative data for repeated cognitive assessment: a comparison of different statistical methods. Behavior Research Methods, 45, 1073-1086Download pdf 


Van der Elst, W., Ouwehand, C., van Rijn, P., Lee, N., Van Boxtel, M. P. J., & Jolles, J. (2013). The shortened Raven Standard Progressive Matrices: Item Response Theory-based psychometric analyses and normative data. Assessment, 20, 48-59. Download pdf


Jacobs, H. I. L., Leritz, E. C., Willems, V. J., Van Boxtel, M. P. J., Van der Elst, W., Jolles, J. Verhey, F. R. J., et al (2013). Association between white matter microstructure, executive functions, and  processing speed in older adults: the impact of vascular health. Human Brain Mapping, 34, 77-95. Download pdf


Van der Elst, W., Reed, H., & Jolles, J. (2013). The Logical Grammatical Structures Test: psychometric properties and normative data in Dutch-speaking children and adolescents. The Clinical Neuropsychologist, 27, 396-409. Download pdf


Van der Elst, W., & Jolles, J. (2012). Verbal learning and aging. In N. M. Steel (Ed.), Encyclopedia of the Sciences of Learning (pp. 3397-3400). New York: Springer-Verlag. Download pdf


Van der Elst, W., Dekker, S., Hurks, P., & Jolles, J. (2012). The Letter Digit Substitution Test: Demographic influences and regression-based normative data for school-aged children. Archives of Clinical Neuropsychology, 27, 433-439Download pdf

 

Hoogenhout, E., De Groot, R. H. M., Van der Elst, W., & Jolles, J. (2012). Effects of a comprehensive educational group intervention in older women with cognitive complaints: a randomized controlled trial. Aging and Mental Health, 16, 135-144. Download pdf


Van der Elst, W., Ouwehand, C., van der Werf, G., Kuyper, H., Lee, N., & Jolles, J. (2012). The Amsterdam Executive Function Inventory (AEFI): psychometric properties and demographically-corrected normative data. Journal of Clinical and Experimental Neuropsychology, 34, 160-171. Download pdf


Van der Elst, W., Van Boxtel, M. P. J., & Jolles, J. (2012). Occupational activity and cognitive aging: a case-control study based on the Maastricht Aging Study. Experimental Aging Research, 38, 315-329Download pdf


Van der Elst, W., & Jolles, J. (2012). Werkomgeving en cognitieve veroudering bij leraren: een case-control studie gebaseerd op de Maastrichtse VerouderingsStudie. Neuropraxis, 4, 130-133. Download pdf 


Van der Elst, W., Hoogenhout, E. M., Dixon, R. A., De Groot, R. H. M., & Jolles, J. (2011). The Dutch Memory Compensation Questionnaire: Psychometric properties and regression-based norms. Assessment, 18, 517-529. Download pdf Test sheet


Van der Elst, W., Hurks, P., Wassenberg, R., Meijs, C., & Jolles, J. (2011). Animal Verbal Fluency and Design Fluency in school-aged children: Effects of age, gender, and mean level of parental education, and regression-based normative data. Journal of Clinical and Experimental Neuropsychology,  33, 1005-1015. 
Download pdf


Jacobs, H. I. L., Van Boxtel, M. P. J., Van der Elst, W., Burgmans, S., Smeets, F., Gronenschild, E. H. B. M., Verhey, F. R., Uylings, H. B. M., & Jolles, J. (2011). Increasing the diagnostic accuracy of medial temporal lobe atropy in Alzheimer's Disease. Journal of Alzheimer's Disease, 25, 477-490. Download pdf


Van der Elst, W., Wassenberg, R., Meijs, C., Hurks, P., Van Boxtel, M. P. J., & Jolles, J. (2011). On the mediating effects of pregnancy and birth stress events on the relation between lateral preferences and cognitive functioning in healthy school-aged children. Journal of Clinical And Experimental Neuropsychology, 33, 548-558. Download pdf

  

Van der Elst, W., Meijs, C. J. C., Hurks, P. P. M., Wassenberg, R., Van Boxtel, M. P. J., & Jolles, J. (2011). Lateral preferences and their assessment in school-aged children. Laterality, 16, 207-226. Download pdf


Van der Elst, W., Hurks, P., Wassenberg, R., Meijs, C., Van Boxtel, M. P. J., & Jolles, J. (2011). On the association between lateral preferences and pregnancy/birth stress events in a nonclinical sample of school-aged children. Journal of Clinical And Experimental Neuropsychology, 33, 1-8. Download pdf

 

Hoogenhout, E. M., Van der Elst, W., De Groot, R. H. M., Van Boxtel, M. P. J., & Jolles, L. (2010). The Neurovegetative Complaints Questionnaire in the Maastricht Aging Study: psychometric properties and normative data. Aging and Mental Health, 14, 613-623. Download pdf


Diesfeldt, H. F. A., Van der Elst, W., & Jolles, J. (2009). Klinische bruikbaarheid van categoriegebonden woordproductie voor het onderscheiden van dementie en normale cognitieve veroudering [Category fluency in normal cognitive aging and dementia]. Tijdschrift voor Gerontologie en Geriatrie, 40, 54-71. Download pdf


Van der Elst, W., Van Boxtel., M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2008). A large scale cross-sectional and longitudinal study into the ecological validity of neuropsychological test measures in neurologically intact people. Archives of Clinical Neuropsychology, 23, 787-800. Download pdf  Supplementary material

 

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2008). Is left-handedness associated with a more pronounced age-related cognitive decline? Laterality, 13, 234-254. Download pdf

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2008). Detecting the significance of changes in performance on the Stroop Color-Word Test, Verbal Learning Test of Rey, and Letter Digit Substitution Test after a test-retest interval of three years: the regression-based change approach. Journal of the International Neuropsychological Society, 14, 71-80. Download pdf

 

Van Dijk, K. R. A., Van Gerven, P. W. M., Van Boxtel, M. P. J., Van der Elst, W., & Jolles, J. (2008). No Protective Effects of Education in Normal Cognitive Aging: Results from the 6-year follow-up of the Maastricht Aging Study (MAAS). Psychology & Aging, 23, 119-130. Download pdf 

 

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2007). Assessment of information processing in working memory in applied settings: the paper & pencil memory scanning test. Psychological Medicine, 37, 1335-1344. Download pdf  Supplementary material


Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2006). The Stroop Color-Word Test: influence of age, sex, and education; and normative data for a large sample across the adult age range. Assessment, 13, 62-79. Download pdf  


Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2006). The Concept Shifting Test: Adult normative data. Psychological Assessment, 18, 424-432. Download pdf  Supplementary material 

 

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2006). Normative data for the Animal, Profession and Letter M naming Verbal Fluency Tests for Dutch speaking participants and the effects of age, education, and sex. Journal of the International Neuropsychological Society, 12, 80-89. Download pdf

 

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2006). The Letter Digit Substitution Test: Normative data for 1,858 healthy participants aged 24-81 from the Maastricht Aging Study (MAAS): influence of age, education, and sex. Journal of Clinical and Experimental Neuropsychology, 28, 998-1009. Download pdf


Van der Elst, W. (2006). The Neuropsychometrics of Aging. Normative studies in the Maastricht Aging Study. Neuropsy publishers, Maastricht (ISBN-13: 978-90-75579-29-1). Download pdf


Van der Elst, W., Van Boxtel, M. P. J., & Jolles, J. (2006). Psychometric analyses of the d2 (Aufmerksamkeits Belastung Test). Published in Brickenkamp, R. (2007). D2 Aandachts- en concentratietest. Hogrefe, Amsterdam. More information (in Dutch)

 

Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2005). Rey’s Verbal Learning Test: Normative data for 1,855 healthy participants aged 24-81 years and the influence of age, sex, education, and mode of presentation. Journal of the International Neuropsychological Society, 11, 290-302. Download pdf

Last update: February 19th, 2023